'VIOXX' definitions:
Definition of 'Vioxx'
From: WordNet
noun
A Cox-2 inhibitor (trade name Vioxx) that relieves pain and inflammation without harming the digestive tract; voluntarily withdrawn from the market in 2004 [syn: rofecoxib, Vioxx]
Definition of 'VIOXX'
From: GCIDE
- VIOXX \VI`OXX\ (v[imac]"[o^]ks), prop. n. [Trade name, used by Merck & Co.] (Chem. & Med.) A trade name for rofecoxib. [Trade name] [PJC]
Definition of 'Vioxx'
From: GCIDE
- rofecoxib \rofecoxib\ (Chem. & Med.) A chemical substance (C17H14O4S, molecular weight 314.36) used in medicine as an analgesic to alleviate pain and inflammation; it is a synthetic compound, and is marketed by Merck & Co. under the trade name Vioxx, in tablets giving dosages of 12.5 or 25 milligrams. It is classed as a non-steroidal anti-inflammatory drug (NSAID). Chemically, it is 4-[4-(methylsulfony)phenyl]-3-phenyl-2(5H) furanone. Its chemical structure contains two phenyl rings and a furanone ring. It is believed to act by inhibition of prostaglandin biosynthesis, through inhibition of the enzyme cyclooxygenase-2 (COX-2); unlike aspirin, it does not inhibit cyclooxygenase-1. [PJC]