'In despite of' definitions:

Definition of 'In despite of'

From: GCIDE

Despite \De*spite"\, n. [OF. despit, F. d['e]pit, fr. L. despectus contempt, fr. despicere. See Despise, and cf. Spite, Despect.]
1. Malice; malignity; spite; malicious anger; contemptuous hate. [1913 Webster]
With all thy despite against the land of Israel. --Ezek. xxv. 6. [1913 Webster]
2. An act of malice, hatred, or defiance; contemptuous defiance; a deed of contempt. [1913 Webster]
A despite done against the Most High. --Milton. [1913 Webster]
In despite, in defiance of another's power or inclination.
In despite of, in defiance of; in spite of. See under Spite. "Seized my hand in despite of my efforts to the contrary." --W. Irving.
In your despite, in defiance or contempt of you; in spite of you. [Obs.] [1913 Webster]